In the early phase of Alzheimer’s disease, astrocytes are the primary source of APOE in the brain. This study examined the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Substrate specificity determines protease ...

After axotomy, severed axons and their synapses engange Wallerian degeneration (WD) to initiate their demise within a day.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The mevalonate pathway produces essential ...

Hypoglycemia is an extremely common side effect of insulin therapy experienced mainly by patients with type 1 diabetes ...

In conclusion, this intriguing report builds on the work of many other groups by further unraveling MECP2 function in the ...

A new resource by Rappe et al (2024) now provides a spatiotemporal landscape of mitophagy changes during mouse brain aging at ...

Eicosapentaenoic acid (EPA) prevents diabetic cardiomyopathy (DC) by promoting the transition of macrophages from M1 to Mox ...

The hair follicle is thought to be a site of ‘immune privilege,’ or relative protection from autoimmune and inflammatory responses. In particular, the long-lived, quiescent hair follicle stem cells ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Lipid droplets (LDs) serve as crucial hubs for ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. T cell receptors (TCR) and gene expression ...