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The EMBO Journal
3 天
Neural precursor cells rescue symptoms of Rett syndrome by activation of the Interferon γ ...
To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was ...
The EMBO Journal
3 天
SUMOylation of protein phosphatase 5 regulates phosphatase activity and substrate release
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...
The EMBO Journal
4 天
Liver protects neuron viability and electrocortical activity in post-cardiac arrest brain ...
The liver function in post-cardiac arrest brain injury is not known and was investigated in a pig model of global cerebral ...
The EMBO Journal
4 天
Astrocyte allocation during brain development is controlled by Tcf4-mediated fate restriction
Astrocytes in the brain exhibit significant regional diversity, but the mechanisms controlling their heterogeneity remain ...
The EMBO Journal
4 天
A shorter splicing isoform antagonizes ZBP1 to modulate cell death and inflammatory responses
Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...
The EMBO Journal
5 天
Reduction of chromosomal instability and inflammation is a common aspect of adaptation to ...
RPE-1 cells adapt to aneuploidy in vitro, a process characterized by reduced CIN and inflammation. This study shows that this ...
The EMBO Journal
5 天
Acetylation of TIR domains in the TLR4-Mal-MyD88 complex regulates immune responses in sepsis
Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...
The EMBO Journal
5 天
miRNA-mediated control of gephyrin synthesis drives sustained inhibitory synaptic plasticity
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...
The EMBO Journal
5 天
Cytoplasmic FBXO38 mediates PD-1 degradation
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback.
The EMBO Journal
6 天
Goliath, meet David
K Heran Darwin is at New York University Grossman School of Medicine and a regular columnist for EMBO reports.
The EMBO Journal
7 天
Tissue-aware interpretation of genetic variants advances the etiology of rare diseases
A machine-learning method predicts whether a genetic variant is pathogenic and affects certain human tissues. The ...
The EMBO Journal
7 天
RNA fine-tunes estrogen receptor-alpha binding on low-affinity DNA motifs for ...
RNA modulates transcription factor binding to DNA, though the subsequent effect on transcription remains unclear. The study ...
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