Compared to placebo (dummy medicine), tolvaptan (a class of medicine known as vasopressin 2 receptor antagonists) probably preserves kidney function and slows the increase in total kidney volume; ...

• Non-invasive positive pressure ventilation may lead to an improvement in asthma symptom score, decreased intubation rate, and slightly shorter paediatric intensive care unit stay, but the results ...

There is limited evidence on the benefits of vitamin D supplements for adults with obesity after weight-loss surgery. We are not confident that taking high or moderate doses of vitamin D after ...

Cochrane is excited to announce that its flagship event, the Cochrane Colloquium, will be hosted in India in October 2026. Building on the momentum of previous successful gatherings, including the ...

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Mike: Hello, I’m Mike Clarke, Podcast Editor for the Cochrane Library. Ankle fractures are one of the most common fractures of the lower limb and it’s important to have evidence on how to help people ...

Assistive technologies are devices that use electrical currents or mechanical means (e.g. splinting) to stretch muscles and soft tissues.

• Multicomponent interventions probably lead to a small increase in eating of fruit and vegetables in children aged five years and under. • Parent nutrition education interventions may lead to little ...

• Acute kidney injury occurs when the kidneys suddenly lose their ability to filter waste from the blood. Erythropoietin-stimulating agents are medicines that are mainly used to treat problems with ...

Tumour necrosis factor-alpha (TNF-a) is a cytokine. A cytokine is a small protein. TNF-a is involved in inflammation. Drugs such as infliximab, etanercept, and adalimumab inhibit TNF activity and ...

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effects of immune checkpoint inhibitors (single-agent or combination therapy) in people with ...