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网页Gut is a Plan S compliant Transformative Journal.. Gut is a leading international journal in gastroenterology and hepatology and has an established reputation for publishing first class clinical research of the alimentary tract, the liver, biliary tree and pancreas.Gut delivers up-to-date, authoritative, clinically oriented coverage in all areas of …
Gut microbiome and health: mechanistic insights | Gut
网页The gut microbiota is now considered as one of the key elements contributing to the regulation of host health. Virtually all our body sites are colonised by microbes suggesting different types of crosstalk with our organs. Because of the development of molecular tools and techniques (ie, metagenomic, metabolomic, lipidomic, metatranscriptomic), the complex interactions occurring between the ...
What defines a healthy gut microbiome? | Gut
网页2024年9月25日 · A wider perspective on gut health considers the absence of digestive complaints as a key indicator. Symptoms like bloating, gas, irregular bowel movements and discomfort may not always be linked to a specific disorder but can indicate suboptimal gut health ().Therefore, a healthy gut, by this definition, is not only ‘free from diagnosed diseases’ but also ‘operates without causing any ...
British Society of Gastroenterology guidelines on the diagnosis …
网页Gastric adenocarcinoma carries a poor prognosis, in part due to the late stage of diagnosis. Risk factors include Helicobacter pylori infection, family history of gastric cancer—in particular, hereditary diffuse gastric cancer and pernicious anaemia. The stages in the progression to cancer include chronic gastritis, gastric atrophy (GA), gastric intestinal metaplasia (GIM) and dysplasia. The ...
The gut microbiota and host health: a new clinical frontier
网页Box 2 Potential therapies aimed at modulation of the gut microbiota. Probiotics: Live microorganisms that, when administered in adequate amounts, confer a health benefit on the host.107, 108 Examples include strains of the genera Bifidobacterium and Lactobacillus.Probiotics can have multiple interactions with the host,109 including competitive inhibition of other microbes, effects on mucosal ...
Human gut microbiome: hopes, threats and promises | Gut
网页The microbiome has received increasing attention over the last 15 years. Although gut microbes have been explored for several decades, investigations of the role of microorganisms that reside in the human gut has attracted much attention beyond classical infectious diseases. For example, numerous studies have reported changes in the gut microbiota during not only obesity, diabetes, and liver ...
Gut microbiota composition reflects disease severity and …
网页Objective Although COVID-19 is primarily a respiratory illness, there is mounting evidence suggesting that the GI tract is involved in this disease. We investigated whether the gut microbiome is linked to disease severity in patients with COVID-19, and whether perturbations in microbiome composition, if any, resolve with clearance of the SARS-CoV-2 virus. Methods In this two-hospital cohort ...
British Society of Gastroenterology guidelines on the management …
网页Irritable bowel syndrome (IBS) remains one of the most common gastrointestinal disorders seen by clinicians in both primary and secondary care. Since publication of the last British Society of Gastroenterology (BSG) guideline in 2007, substantial advances have been made in understanding its complex pathophysiology, resulting in its re-classification as a disorder of gut-brain interaction ...
Multiomics of the intestine-liver-adipose axis in multiple studies ...
网页4 天之前 · Background The microbiota is emerging as a key factor in the predisposition to insulin resistance and obesity. Objective To understand the interplay among gut microbiota and insulin sensitivity in multiple tissues. Design Integrative multiomics and multitissue approach across six studies, combining euglycaemic clamp measurements (used in four of the six studies) with other measurements of ...
Six-month follow-up of gut microbiota richness in patients with …
网页The gut microbiota richness, measured by Chao 1 index, was obviously lower (p<0.01, Wilcoxon rank-sum test; figure 1A) in the acute phase of COVID-19 (median 217, IQR 164–266) as compared with uninfected controls (median 432, IQR 332–468).There was a non-significant increase of the Chao 1 index from the acute phase (median 217, IQR 164–266) to the convalescence (median 241, IQR 202–279 ...